Immune System


Fact: A weakened Immune System leaves you vulnerable to serious diseases and disorders

  • Cancers:
    • Breast Cancer
    • Prostate Cancer
    • Lung Cancer
    • Colon Cancer and Rectal Cancer
    • Ovarian Cancer and Endometrial Cancer
    • Recurrent and Advanced Metastatic Cancers
  • Infectious Diseases:
    • Bacterial (M. tuberculosis, E. coli, MRSA)
    • Viral (Influenza, Herpes, HIV/AIDS)
    • Poor response to vaccination
  • Coronary Heart Disease and Heart Attack
  • Cerebrovascular Disease and Stroke
  • Alzheimer’s Disease
  • Metabolic Syndrome and Type II Diabetes
  • Depression and Chronic Fatigue Syndrome
  • Autoimmune disorders:
    • Rheumatoid Arthritis
    • Inflammatory Bowel Disease
    • Crohn’s Disease

 

The Immune System

The human body has a built-in ability to protect itself from harm. The complex interactions of the immune system protect us against invasion by foreign agents, and also dispose of cells that have been infected or transformed into Cancer cells.

It is an undeniable fact that maintaining a strong, vital immune system is a key component of good health, high quality of life and enjoying longevity.

However, many factors can suppress immune function. Most of these factors are a common part of everyday modern life:

  • Insufficient Sleep
  • Insufficient Exercise
  • Stressful Relationships
  • Stress in the Home and Workplace
  • Poor Diet and Inadequate Nutrition
  • Exposure to Environmental Pollution (…TØXIC…)
  • Drugs and Prescription medications

Due to these factors and the hectic pace of our lifestyles, it is often difficult for us to obtain all of the nutrients necessary for our body and immune system to operate at optimum levels.

Levels of Protection

The immune system has three primary levels of protection.

Level One: The first level is simply physical barriers, such as the skin and mucous membranes.
Level Two: When pathogens make it past the physical barriers, the second level of defense is called to action. This branch of immunity is called the Innate Immune System because of its ability to act without prior exposure to identify and destroy Cancers, microbial pathogens and other dangerous intruders. It is primarily comprised of the following components:

  • Natural Killer (NK) cells: These cells are like rapid deployment Special Forces units which provide the first line of defense within the body. NK cells respond immediately to track down and eliminate Cancer and infected cells, and other damaging invaders.
  • Macrophages: Literally translated as “large eaters,” macrophages eat up pathogens and clean away cellular debris.
  • Cytokines: These molecular messengers of the immune system enable the cellular defenses to communicate with each other.
Level Three: When pathogens make it the second level of defense, the body launches the third and most critical level of defense – the Adaptive Immune System, which includes the following components:

  • T cells: T cells are highly specialized white blood cells called lymphocytes. Killer T cells kill infected or abnormal cells, while helper T cells act as “immune system managers,” telling other cells what to do. When T cells are severely compromised by infection with HIV, the cells develop AIDS.
  • B cells: Like T cells, B cells are also white blood cells called lymphocytes. Their function is to make antibodies, which are highly specialized proteins that the immune system uses to identify and eradicate pathogens, harmful cells and foreign substances.

Aging

What is Aging? Is Aging inevitable? Is Aging a scientific fact, a statistical tendency, or widely-accepted belief?

Is Aging a natural function of human life and physiology, or is it a condition brought on by a disorder in human lifestyle and physiology?

If Aging is truly a process that is primarily governed by genetics and the linear passage of time, then should it would be a common and prevalent occurrence for identical twins – humans of identical chronological age that are considered to possess identical genetics – to die on the same day, minutes or hours apart. But this is not the case.

Immunity against Aging

The term “Aging” is typically defined as the gradual decline in one’s well-being and quality of life, characterized by an increased incidence and severity of debilitating chronic diseases. The current scientific literature on Immunity and Aging, as well as Neuropsychology have built a body of evidence which finds human immune system dysregulation – termed “Immunosenescence” – may be the key determining factor in the majority of the diseases and disorders which are accepted as being Aging-related such as Cancer, Depression, Cardiovascular Disease and Heart Attacks, Cerebrovascular Disease and Stroke, Alzheimer’s Disease, Metabolic Syndrome and Diabetes, Rheumatoid Arthritis and Osteoarthritis.

Aging can now be seen from an immune system perspective, as a chronic dysregulation of human immune cellular functions and an inappropriate increase in inflammatory activity throughout the body. This combined circumstance then predisposes the human body to multiple system failure and global demise.

Quality of Life

Healthful Longevity

There is a vast body of scientific literature which indicates that immune dysregulation – specifically in that branch of the immune system referred to as the “innate” – may be the determinative factor for the seemingly inevitable functional decline of advancing age. This dysregulation is characterized by an over-reactive state of systemic immune processes which promotes the changes typical of many of the chronic diseases which we associate with Aging.

The scientific findings from our Research Fellows and the world literature indicate that it should be possible to alter the aging process. By restoring optimal immune function, we now can realistically plan to impact human longevity by effectively immunizing ourselves against Aging itself.

Immunosenescence

Current research shows that, like the brain, the Immune System can become senile. This process is known as “Immunosenescence”, the condition of decline in immune function as you grow older. Quite surprisingly, this decline typically begins early in life, and then worsens as we advance in age.

THE CONCEPT: Immunosenescence

Immunosenescence is an insidious process which leads to:

  • Impaired responses to antigen exposure
  • Increased infectious disease morbidity and mortality
  • Increased incidence of Cancers, Vascular Diseases, and Autoimmune Disorders

THE PHENOMENON: Immunosenescence

Immunosenescence also involves the inflammatory changes which can be important determinative factors in chronic diseases and general frailty associated with Aging including:

  • Advanced Cancers and Metastases
  • Coronary Heart Disease and Heart Attacks
  • Cerebrovascular Disease and Strokes
  • Alzheimer’s Disease (Presenile Dementia)
  • Inflammatory Bowel Disease and Crohn’s Disease
  • Metabolic Syndrome and Diabetes
  • Osteoarthritis and Osteoporosis
  • Rheumatoid Arthritis

Immunosenescence is primarily characterized by a gradual depression of cellular functions throughout the immune system. It has been shown scientifically to be directly associated with a phenomenon called “telomere shortening”, which weakens our ability to produce the new immune cells needed to protect the body from disease. Immunosenescence can also provoke the development of autoimmune disorders.

Natural Killer (NK) Cells

The cells most severely affected are Natural Killer (NK) cells, the body’s first line of defense against Cancer, microbial infections, and many other serious diseases. Many scientific studies also show a link between NK cell deficiency and autoimmune diseases, susceptibility to Lyme Disease, and Chronic Fatigue Immune Dysfunction Syndrome (CFID). People with NK cell deficiency also show increased susceptibility to phases of Herpes virus and influenza virus infection and recurrence.

Cancer

The current scientific evidence clearly indicates that advancing age is the single greatest risk factor for the development of cancer. Specifically, the incidence of cancer increases in advanced adults who demonstrate age-dependent progressive Immunosenescence and its resultant NK cell deficiency.

Natural Killer (NK) cells are specifically known to kill invasive tumor cells. They accomplish this task by binding themselves to cancer cell membranes and injecting powerful enzyme granules which cause the cancer cell to dissolve in death within five minutes.

Infectious Diseases

Immunosenescence is an insidious process which weakens human immunity against exposure to viruses (e.g., Influenza), bacteria (e.g., E. coli) and other infectious microbes. Among other factors, it is the NK cell deficiency which leads to an increased severity of illness and death rate from infectious diseases.

Coronary Heart Disease

Viral and bacterial infections are now recognized as major risk factors for Coronary Heart Disease (CHD). As the first line of defense against those infections, a weakened and depleted NK cells may open the door to the development of CHD.

Immunomodulators

A true modulator of immune function – an Immunomodulator – is an agent that functions to strengthen or restore immune activity as needed to optimize health. Optimizing immune function via internal regulatory signals and control systems is termed Immunorestoration.

Immunorestoration

When the immune system is weakened or overactive due to aging, lifestyle, environmental toxins, or other causes of deficiency, we become more susceptible to viral and bacterial infections like influenza and the common cold, as well as Heart Disease and Cancer. Immunorestoration is an approach to remedy the effects of Aging and Immunosenescence, and revitalize the body’s natural immune response and anti-cancer immunity.

In clinical studies of these and other conditions, it has been shown that certain Immunomodulator Compounds can up-regulate, and so improve a weakened immune response. As well, in conditions where the immune system is overactive and harming the body, RBAC Immunomodulator Compounds have been shown to down-regulate immune system. In the specific case of Autoimmune Diseases, the immune system is overactive, and preliminary evidence indicates that RBAC has a restorative, down-regulating effect.